Background: Health promotion is particularly important for postmenopausal women, since healthy behaviors such as regular exercises and stress management can effectively reduce the severity of health problems and discomforts associated with postmenopausal. Aim: The present study aimed to assess health promoting lifestyle behaviors among post-menopausal women. Design: A descriptive design was utilized to conduct the present study. Setting: The study was conducted at Kafr Badran village in Sharqia Governorat Sample: A purposive sample composed of 120 postmenopausal women. Tools: two tools were used in the present study. Tool I: A structured interview questionnaire consisted of three parts; Part one: Demographic characteristics of the studied postmenopausal women, Part two: Menstrual, obstetrical, gynecological and contraceptive history of the woman; Part three: Women knowledge regarding menopause .Tool II: Health Promotion Lifestyle Profile. Results: the present study results revealed that 90% of studied postmenopausal women had unsatisfactory level of knowledge about the menopause, 55% of the postmenopausal women had moderate health promotion lifestyle profile level. Conclusion: there was a statistically significant positive correlation between knowledge and health promotion lifestyle profile. Recommendations: Designing awareness programs and counseling sessions for postmenopausal women aimed at empowering them to engage in health-promoting behaviors.