Different ecosystems can be exposed to pesticide residues, which pose a huge threat to the environment and to non-target organisms which includes useful soil microorganisms, plants, and human. In addition, pesticides have a negative impact on rhizobacteria’s plant-useful functions, resulting in reduced nodulation in legumes, reduced N accumulation in grains, and a poor impact on grass root improvement, because of cell death of microbial as a result of pesticides. Undoubtedly, one of the main challenges is the compatibility of pesticides and inoculants, so new procedures to resolving the pesticide-inoculant incompatibility are required. Plant growth promoting rhizobacteria (PGPR) can be utilized as excellent and effective biotechnological tools and they represent promising long-term solutions for improving plant biomass production and reducing the harmful phytotoxic effects of organic pollutants. Furthermore, PGPR can improve degradation of pesticide residues and other contaminants, increasing the bioavailability of xenobiotics in the rhizosphere area and plant uptake subsequently for providing a clean environment free of contaminant and alternative to hazardous chemical fertilizers. Interactions of both plants and bacteria with catabolic genes have resulted in the emergence of more than one catabolic enzyme able to metabolize and detoxify xenobiotics as a sole carbon source for their cell functioning and metabolism. By growing powerful, adaptable and versatile bacterial strains and improving handling facilities/processing technologies, advanced biotechnology, microbiology, and genetic engineering can contribute to solving the problem of pesticide bioremediation. More cooperation is required between scientists who contribute to the field of environmental remediation, such as genetics, biochemists, microbiologists, and the environment.KeywordsPlant growth promoting rhizobacteria (PGPR)Pesticide residuesRemediationRecent trends Read more