Grasshoppers are major pests of agriculture throughout much of the world. Chemical control of grasshoppers played a major role in suppression the damage of these pests. Efficacy of some chemical insecticide formulations was studied against 3rd, 4th and 5th nymphal instars and adults of different species of grasshoppers at the region of Gharb El-Mawhoop, New-Valley governorate, Egypt by using micron ULVA sprayer (ULVA+), Knapsack mist blower fifed with micron air rotary cage (AU8000) and Knapsack mist blower (ordinary back motor). Mortality percentages were calculated after 24, 48 and 72 hrs post- treatment for chemical insecticide treatments. The results indicated that Knapsack mist blower fitted with micron air rotary cage (AU8000) was more effective against 3rd, 4th and 5th nymphal instars and adults of grasshoppers than micron ULVA sprayer (ULVA+) for all treatments. Cypermethrin, fipronil, and fenitrothion recorded more toxicity after 24, 48 and 72 hrs by using full doses more than half doses or quarter doses against nymphal instars and adult stages of grasshoppers, despite of that, the application with half dose give mortality percentages approximately as the full dose, which resulted in reduction of the amount of pesticides and declined pollution of environmental ecosystems, so it is preferable to use the Conclusively, from this results it could be concluded that the pesticides used have been descendingly arranged according to the efficiency as cypermethrin> fipronil > fenitrothion at all the treatments half dose for saving money and low pollution.