Soluplus® as a solubilizing excipient for poorly water-soluble drugs: Recent advances in formulation strategies and pharmaceutical product features

Faculty Pharmacy Year: 2023
Type of Publication: ZU Hosted Pages:
Authors:
Fakhreldeen Soliman Ghazy Shehata
Journal: Journal of Drug Delivery Science and Technology Elsevier Volume:
Keywords : Soluplus® , , solubilizing excipient , poorly water-soluble drugs:    
Abstract:
Since the emergence of Soluplus® (SOL) as a commercial graft copolymer, several publications have been issued on its promising potential as a solubilizing excipient that could promote the dissolution rate and bioavailability of several poor
    
     
 
       

Author Related Publications

  • Fakhreldeen Soliman Ghazy Shehata, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Fakhreldeen Soliman Ghazy Shehata, "Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues", Elsevier, 2019 More
  • Fakhreldeen Soliman Ghazy Shehata, "Pediatric suppositories of sulpiride solid dispersion for treatment of tourette syndrome :invitro and invivo investigations", ِِِِِAAPS pharm tech, 2014 More
  • Fakhreldeen Soliman Ghazy Shehata, "Solid dispersion approach for optimized bioavailability of sulpiride", Lat.Am.j.Pharm, 2013 More
  • Fakhreldeen Soliman Ghazy Shehata, "Formulation and pharmaceutical evaluation of metoclopramide HCL floating capsules", IJAPR, 2013 More

Department Related Publications

  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from Hypericum revolutum in Rat Aorta", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Nora Ahmed Ahmed Mohamed Hsaan, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Interference with TGF beta 1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Rp-HPLC Determination of Quercetin in a Novel D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
Tweet