Background: A COVID-19 pandemic is emerging infections and a horrible disease has been shown to have a fatal impact on pregnant women and their fetuses. Aim of this study: was to evaluate effect of educational nursing intervention based on health beliefs model on prevention of COVID-19 among pregnant women. Study design: A quazi -experimental design was used. Setting: the study was conducted in Obstetrics and Gynecology clinic (antenatal unit) in outpatient clinics at Zagazig University Hospital. Subject: A purposive sample composed of 195 pregnant women. Tools of data collection: four tools were used: Tool I: An interview questionnaire; Tool II: pregnant women's knowledge questionnaire regarding COVID-19; Tool III: pregnant women's practice for self-protective measures in relation to prevention COVID-19 and tool IV: health belief model regarding COVID-19. Results: the current study revealed that mean age of pregnant women was 33.74±6.51 years old. Furthermore, there was highly statistically significant difference of studied pregnant women regarding total mean score of knowledge, practice and health belief at post intervention (P= 0.000**) as well there was statistically significance correlation between total knowledge, practice of self-protective measure and health belief model among studied pregnant women throughout intervention where (P <0.05). Conclusion: it was concluded that implementation of heath educational program based on health belief model regarding the COVID 19 pandemic showed a positive impact and effective improvement of knowledge, self- protective measure practices and health belief regarding prevention of COVID 19 among pregnant women. Recommendations: Heath educational intervention regarding prevention for COVID-19 should be provided for all pregnant women at all MCH centers until the total management of COVID-19 virus.