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Diffusion Weighted Magnetic Resonance Imaging in Evaluation of Non Muscle Invasive Bladder Cancer Correlated to the Second Cystoscopy
Faculty
Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Majid Mohamed Ali Mahmoud Aawad
Staff Zu Site
Abstract In Staff Site
Journal:
European Journal of Molecular & Clinical Medicine International
Volume:
Keywords :
Diffusion Weighted Magnetic Resonance Imaging , Evaluation
Abstract:
Background: Proper management of the urinary bladder cancer depends on the stage of the lesions. The aim of this work was to correlate between the outcomes of DW-MRI results and biopsy results of 2nd look TURBT in NMIBC and to correlate between DW-MRI and conventional MRI in NMIBC. Patients and methods: It was a prospective study included twenty four patients with NMIBC underwent 2nd look TURBT with preoperative imaging with DW-MRI on pelvis. Bladder mapping was done on 1.5 T Philips Achieva system class II MRI device is used. T1andT2 weighted is used for anatomical and morphological evaluation. Diffusion-weighted images were obtained by using single shot echoplanar imaging with a pair of rectangular gradient pulses along three orthogonal axes. Second look cystoscopy and biopsy was performed under spinal anesthesia. Resection of lateral wall bladder tumors was performed under general anesthetic with a paralytic agent to avoid inadvertent bladder wall perforation from an obturator nerve reflex .Biopsy was taken from the tumor base or residual of the mass if present for histopathological examination Results: Sensitivity of DW-MRI was 100%, specificity was 92.8% and accuracy was 96.8% in prediction of malignancy, while Sensitivity of DW-MRI was 83.33%, specificity was 80% and accuracy was 81.25% in prediction of muscle invasion tumors. 14 of the 32 lesions analyzed in the second TURB were diagnosed as MIBC. There was a significant correlation between clinical staging by DW-MRI and pathological staging
Author Related Publications
Majid Mohamed Ali Mahmoud Aawad, "Evaluation of multimodal therapy using endoscopic resection with concurrent gemcitabine and radiotherapy in the treatment of muscle invasive bladder cancer", Zagazig University Medical Journal, 2014
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Majid Mohamed Ali Mahmoud Aawad, "The Prognostic Role of NEDD9 and P38 Protein Expression Levels in Urinary Bladder Transitional Cell Carcinoma", Journal of Oncology, 2017
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Majid Mohamed Ali Mahmoud Aawad, "Prognostic implication of MYb-like, swirm and Mpn domain-containing protein-1 and Twist-1 in renal cell carcinoma", Journal of Interdisciplinary Histopathology, 2017
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Majid Mohamed Ali Mahmoud Aawad, "Bladder preservation by neoadjuvant chemotherapy followed by gemcitabine as radiosensitizer for muscleinvasive transitional cell carcinoma of the urinary bladder after maximal TURBT", Cancer Biology journal, 2015
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Majid Mohamed Ali Mahmoud Aawad, "W-pouch With Modified Non-isolated Extra Limb for Continence in Cutaneous Diversion After Radical Cystectomy", International, 2017
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Department Related Publications
Mahmoud Mohamed Mahmoud Eladl, "Immunologic Factors in Recurrent Urinary Calculi of Bilharzial patients", Zagazig university medical journal, 1983
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Amro Mohamed Fawzy Ibrahiem Eldesouky, "The roleofneuralprecursorcell-expresseddevelopmentally down-regulated protein9inpredictingbacillusCalmette-Guerin response innonmuscleinvasivebladdercancer", Elsevier, 2018
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Mohammed Salahuddin Rizk Dirie, "Outcome of docetaxel in treatment of metastatic hormone-sensitive prostate cancer and correlation with hemoglobin, albumin, lymphocyte and platelets score نتيجة الدوسيتاكسيل في علاج سرطان البروستاتا المنتشر الحساس للعلاج الهرمونى والارتباط مع نقاط الهيموجلوبين والألبومين والخلايا الليمفاوية والصفائح الدموية", Contemp Oncol (Pozn)., 2022
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Ahmed Alayman Abdelaal Ahmad, "دور جراحة دوالى المجهرية تحت الفتحة الاربعية الخارصية فى تقليل مضاعفات الجراحة التقليدية", لايوجد, 1900
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Ahmed Alayman Abdelaal Ahmad, "دراسة معملية اكلينكية على تاثير الفلافوكسات بالمقارنة مع البروباثلين ", لايوجد, 1900
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