Diffusion Weighted Magnetic Resonance Imaging in Evaluation of Non Muscle Invasive Bladder Cancer Correlated to the Second Cystoscopy

Faculty Medicine Year: 2021
Type of Publication: ZU Hosted Pages:
Authors:
Journal: European Journal of Molecular & Clinical Medicine International Volume:
Keywords : Diffusion Weighted Magnetic Resonance Imaging , Evaluation    
Abstract:
Background: Proper management of the urinary bladder cancer depends on the stage of the lesions. The aim of this work was to correlate between the outcomes of DW-MRI results and biopsy results of 2nd look TURBT in NMIBC and to correlate between DW-MRI and conventional MRI in NMIBC. Patients and methods: It was a prospective study included twenty four patients with NMIBC underwent 2nd look TURBT with preoperative imaging with DW-MRI on pelvis. Bladder mapping was done on 1.5 T Philips Achieva system class II MRI device is used. T1andT2 weighted is used for anatomical and morphological evaluation. Diffusion-weighted images were obtained by using single shot echoplanar imaging with a pair of rectangular gradient pulses along three orthogonal axes. Second look cystoscopy and biopsy was performed under spinal anesthesia. Resection of lateral wall bladder tumors was performed under general anesthetic with a paralytic agent to avoid inadvertent bladder wall perforation from an obturator nerve reflex .Biopsy was taken from the tumor base or residual of the mass if present for histopathological examination Results: Sensitivity of DW-MRI was 100%, specificity was 92.8% and accuracy was 96.8% in prediction of malignancy, while Sensitivity of DW-MRI was 83.33%, specificity was 80% and accuracy was 81.25% in prediction of muscle invasion tumors. 14 of the 32 lesions analyzed in the second TURB were diagnosed as MIBC. There was a significant correlation between clinical staging by DW-MRI and pathological staging
   
     
 
       

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