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Holmium laser versus cold knife visual internal urethrotomy for management of short segment urethral stricture: a prospective randomized clinical trial
Faculty
Medicine
Year:
2023
Type of Publication:
ZU Hosted
Pages:
Authors:
Majid Mohamed Ali Mahmoud Aawad
Staff Zu Site
Abstract In Staff Site
Journal:
World Journal of Urology International
Volume:
Keywords :
Holmium laser versus cold knife visual internal
Abstract:
Objectives To report the safety and efcacy of holmium laser and compare its results with cold knife visual internal urethrotomy (VIU) in the management of short segment urethral stricture. Methods This prospective randomized study included 66 male patients aged more than 18 years, with short segment bulbar urethral strictures<2 cm from March 2020 to March 2022. The patients were randomized into two groups each containing 33 patients. In group A (Cold knife group), Sachse cold knife was used for stricture treatment. In group B (Holmium group), internal urethrotomy was done with Ho:YAG laser. Patients were evaluated before the operation and followed up after the operation at 1, 3, 6 and 12 months by physical examination, IPSS, PVR, Qmax and retrograde urethrography. Results There was signifcant improvement in the mean values of IPSS, PVR and Qmax in both groups. There was no signifcant diference between both groups in the mean values of IPSS, PVR and Qmax during follow-up visits. However, at the end of follow-up at one year there was statistically signifcant diference between both groups in the mean values of IPSS, PVR and Qmax due to higher recurrence rate in cold knife group than laser group. The overall complication rate is signifcantly lower in laser group (p=0.014). Conclusion Holmium laser VIU is an efective and safe treatment option for short segment urethral stricture with shorter operative time, less complication rate and less recurrence than cold knife VIU.
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