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Prediction of high-risk oesophageal varices in patients with compensated cirrhosis using albumin-bilirubin-platelet score
Faculty
Medicine
Year:
2022
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Lotfy Mohamed Zaki Sharf
Staff Zu Site
Abstract In Staff Site
Journal:
European Journal of Gastroenterology and Hepatology Wolters Kluwer Health, Inc.
Volume:
Keywords :
Prediction , high-risk oesophageal varices , patients with
Abstract:
Background: Despite the fact that endoscopy is the gold standard for screening of high-risk varices (HRVs) in patients with compensated cirrhosis, it is invasive, costly and not necessary for all patients. So, noninvasive tests can replace endoscopy. We aimed at evaluating the albumin-bilirubin-platelet (ALBL-PLT) score as a noninvasive test in predicting HRVs in compensated cirrhotic patients versus Baveno VI and extended Baveno VI criteria. Methods: patients with compensated cirrhosis (n = 204) were included. Laboratory parameters, esophagogastroduodenoscopy (EGD) and liver stiffness measurement by transient elastography were done. Classification of patients according to the status of HRVs was done. We compared both groups on the basis of ALBL-PLT score, Baveno VI and extended Baveno VI criteria. Results: Among the total patients, 96/204 (47%) patients had HRVs. They have higher liver stiffness measurement than those without HRVs (33 ± 13.1 versus 19.3 ± 8.25, CI, −19.94, −7.31, P value <0.001). Also, all HRVs patients have an ALBL-PLT score of more than 3. The area under the receiver operating characteristic curve for the ALBL-PLT score is higher than that for Baveno VI and extended Baveno VI criteria (0.894 versus 0.722 and 0.792, respectively). Conclusion: ALBL-PLT score of more than three has a good predictive value in predicting HRVs among compensated cirrhotic patients.
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Department Related Publications
Ahmed Mohamed Mahmoud ebrahym, "تقييم الاختبار الانزيمى المناعى ( الإليزا ) فى كشف مولدات المضادات ( أنتجين ) لميكروب السالمونيلا فى مرضى الكباد البلهارسى ", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "دراسة المؤشرات المصليه لفروسات الإلتهاب الكبدى قبل وبعد الجراحه ", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "المغزي الاكلينيكي لمادة الثرمبوموديولين في بعض الحالات المسببة لالتهاب القولون.", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "حساسية ميكروبات السالمونيلا المتسبب فى الحمى المعوبة للسيرو فلوكساسين والعقاقير التقليدية الأخرى", لايوجد, 1900
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Ibrahiem Mohamed Ibrahim Mohamed Hegazy, "مدى انتشار الالتهاب الكبدى الوبائى ( س ) بين مجموعة من الأشخاص العسكريين المصابين بالالتهاب الكبدى الحاد", لايوجد, 1900
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