Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Study of Urinary Angiotensinogen as an Indicator of Severity of Diabetic Nephropathy in Type 2 Diabetes
Faculty
Medicine
Year:
2023
Type of Publication:
ZU Hosted
Pages:
Authors:
Staff Zu Site
Abstract In Staff Site
Journal:
zagazig university medical journal zagazig university medical journal
Volume:
Keywords :
Study , Urinary Angiotensinogen , , Indicator , Severity , Diabetic
Abstract:
Background: Urinary angiotensinogen levels are higher in type 2 diabetes patients with nephropathy, a risk factor for developing renal and cardiovascular consequences. However, the potential relationship between serum urine angiotensinogen levels and albuminuria (in terms of its varying concentrations) is not yet established. As a result, we conduct this research. Method: Sixty-six adults with type 2 diabetes were split into three groups, each of which included 22 people based on their degree of albuminuria, in addition to an age- and gender-matched control group of 22 healthy volunteers. Routine laboratory tests and urine angiotensinogen were evaluated in the study groups and correlated to other study parameters. Results: The current study showed that urine angiotensinogen levels are more significant in diabetic patients with higher albuminuria levels, and it was also found to be associated with urinary albumin excretion in diabetic patients with different grades of albuminuria (n = 66, r = 0.666, p<0.001), and it had highly significant validity in the prediction of albuminuria among individuals with diabetes with sensitivity of 88.6%, specificity of 81.8% and accuracy of 86.4%. Conclusions: According to the findings of this study, increased urine angiotensinogen levels were associated with urinary albumin excretion, and elevated urinary angiotensinogen might be utilized as an effective marker for identifying the degree of albuminuria in diabetic individuals.
Author Related Publications
Department Related Publications
Ayman Abdalrahman Mohamed Nasrllah, "Thyroid Dysfunction and Inflammatory Biomarkers in COPD:Relation to Severity and Exacerbation", Cairo,Egypt, 2013
More
Emad Fawzy Hamed Mahmoud, "ANNEXIN A2 VERSUS AFP AS AN EFFICIENT DIAGNOSTIC SERUM MARKER FOR HEPATOCELLULAR CARCINOMA", المجله المصريه الافريقيه للامراض المتوطنه, 2013
More
Emad Fawzy Hamed Mahmoud, "PARAOXONASE 1 Gene Polymorphism Relationship with Type 2 Diabetes Mellitus", life science journal, 2012
More
Ayman Abdalrahman Mohamed Nasrllah, "Microalbuminurea Screening and Risk factors in adolescents with type 1 Diabetes Mellitus In Zagazig University Hospital n", London, 2012
More
Ayman Abdalrahman Mohamed Nasrllah, "Predicting Insulin Resistance Using Triglyceride to High Density Lipoprotein Ratio In Egyptian Adults", Zagazig University,Medical College, 2013
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف