Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Predictors of Reduced Bone Mineral Density in Juvenile Systemic Lupus Erythematosus
Faculty
Medicine
Year:
2023
Type of Publication:
ZU Hosted
Pages:
12
Authors:
Mei Abdel Fattah Mohamed Mouhamed
Staff Zu Site
Abstract In Staff Site
Journal:
geget ESPNT
Volume:
Keywords :
Predictors , Reduced Bone Mineral Density , Juvenile
Abstract:
Introduction: One of the juvenile Systemic Lupus Erythematosus (j-SLE) consequences that lower patients' quality of life is low bone mineral density (BMD). By employing DXA (dual X-ray absorptiometry), BMD is evaluated. Aim: This study's objectives are to research BMD in SLE children and to describe the predicting factors. Methods: A case control study included 30 SLE patients (the SLE group) (mean age, 14.8± 2.5 years; females, 83.3%) and 30 age and sex-matched, seemingly healthy children (the Control group). They had a thorough medical history and clinical examination, as well as laboratory tests, 25(OH) vitamin D levels, and BMD evaluation by DXA scan (scores at L2-L4). The information was presented as mean and standard deviation. The Pearson's correlation and the student t-test were used for statistical analysis.At a p value of 0.05, differences were deemed statistically significant. Results: Low BMD was detected in the SLE group in comparison to the controls (p<0.001). Reduced BMD was detected in 46.6% of patients. Vitamin D level is lower in SLE group with statistically significant difference. On regression analysis; duration of disease, steroid use, and alkaline phosphatase were found to be independent variables that affected BMD. Conclusion: SLE patients frequently have low BMD. A longer course of the illness, and higher overall glucocorticoid dose were powerful predictors of low BMD. The patients may be protected from the possibility of decreased BMD by DXA monitoring and the implementation of an appropriate therapy plan. Key words: Bone mineral density; Systemic lupus erythematosus; dual X-ray absorptiometry
Author Related Publications
Mei Abdel Fattah Mohamed Mouhamed, "Hemodialysis in Children Eleven Years in a Single Center in Egypt", PUBMED, 2013
More
Mei Abdel Fattah Mohamed Mouhamed, "Serum and CSF adiponectin, leptin, and interleukin 6 levels as adipocytokines in Egyptian children with febrile seizures: a cross-sectional study", PUBmed, 2016
More
Mei Abdel Fattah Mohamed Mouhamed, "Interleukin-10 -1082 G/A gene polymorphisms in Egyptian children with CAP. A case–control study", pubMED, 2016
More
Mei Abdel Fattah Mohamed Mouhamed, "Vitamin D receptor gene BsmI polymorphisms in Egyptian children and adolescents with systemic lupus erythematosus A case–control study", PubMed, 2016
More
Mei Abdel Fattah Mohamed Mouhamed, "Association of IL-10 gene polymorphisms and susceptibility to Juvenile Idiopathic Arthritis in Egyptian children and adolescents: a case-control study", PubMed, 2017
More
Department Related Publications
Seham Fathy Abdelhamid Azab, "Serum trace elements in obese Egyptian children: A case-control study", biomedcentral, 2014
More
Seham Fathy Abdelhamid Azab, "IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia", elsevier, 2014
More
Seham Fathy Abdelhamid Azab, "Impact of socioeconomic status on severity and outcome of community acquired pneumonia among Egyptian children: A cohort study", biomedcentral, 2014
More
Seham Fathy Abdelhamid Azab, "Iron deficiency anemia as a risk factor for cerebrovascular events in early childhood: a case-control study.", springer, 2014
More
Seham Fathy Abdelhamid Azab, "Nutritional Biomarkers in Children and Adolescents with Beta-Thalassemia-Major: An Egyptian Center experience", hindawi, 2014
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف