Complicated wounds passively affects the quality of patients life as well as the insult on the health care budget, negative pressure wound therapy ( NPWT), an example of technological application in wound therapy improves the quality of patient life by decreasing pain, frequency of dressing and wound debridement sessions, and hastens wound cleanliness. This is a comparative clinical trial between two groups of patients with complicated abdominal wall wounds; group A (18 patients) treated using (NPWT), and group B (19 patients) treated by conventional methods, demographic criteria, operative and follow up data till wounds become clean collected and analyzed using the proper tests. Analysis of the study data revealed that the use of (NPWT) is significantly better than the conventional methods regarding number of debridement sessions, total dressings number, severity of pain 24 hours post debridement and later on, patient mobilization and total time taken for wounds to be ready for definitive closure. When applicable, (NPWT) can be the ideal method for treating complicated abdominal wall wounds. Keywords; negative pressure, wound management, complicated wounds