Abstract Background: Laparoscopic appendectomy can decrease the incidence of surgical site infection, especially if there is no contact between the appendix specimen and the wound site, the main disadvantage of the retrieval bags is their high cost and relatively the bigger incision they need, the extraction of the appendix through any of the ports directly is limited to the thin non complicated appendix, in this study we tried to evaluate the use of a cuff of a surgical glove tailored as a retrieval bag. Patients and methods: 103 patients undergoing laparoscopic appendectomy were randomized into two groups; group I, 52 patients where surgical glove were used as retrieval bag for extraction of the appendix. Group II, 51 patients where the appendix was extracted directly through the suprapubic port. Preoperative, operative and follow up data were analyzed for comparison between both groups. Results: The demographic and preoperative data are almost comparable between both groups, but operative data shows a significant difference between both groups regarding post-operative intraperitoneal collection higher in the second group (p=0.038) also the rate of the SSI is higher in the second group but statistically insignificant. Conclusion: The use of surgical glove cuff as a retrieval bag during laparoscopic appendectomy is a cheap efficient alternative to the readymade expensive retrieval bags in reduction of intraabdominal and surgical site infections