Use of biochar and nitrogen application timing might be an effective strategy to ‎improve soil properties and increase wheat yield, especially in sandy soils. Giza 171 cultivar exhibited uppermost grain yield, almost yield attributes, nitrogen uptake efficiency (total-NUpE) and NUE followed by Shandwel 1. Biochar application at 6 Mg ha-1 significantly increased grain yield and almost yield attributes, total-NUpE and NUE compared with the control treatment. Adding N fertilizer at T2(10,25,40,55 and 70 DAS) or T3( 10,30,50,70 and 90 DAS) had greatly improved grain yield and yield attributes and nitrogen use efficiencies comparing with T1(10,20,30,40 and 50 days after sowing (DAS) treatment. The interaction between N application timing at T2 and application of 6 Mg biochar ha-1 produced the maximum grain yield (7.23 Mg ha-1) and NUE (55.37 kg kg-1) when Giza 171 was used. Path coefficient analysis showed that spike length and number of spikes m-2 had exerted positive and high direct effect on grain yield of wheat (0.343 and 0.436), while flag leaf area and number of fertile spikeletes spike-1 had positive but moderate direct effect on wheat grain yield (0.280 and 0.201).