Factors Affecting HCC Recurrence Post Liver Resection versus Living Transplantation

Faculty Medicine Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Clinics in surgery Remedy publications LLC Volume:
Keywords : Factors Affecting , Recurrence Post Liver Resection    
Abstract:
Background: Liver resection, liver transplantation and loco-regional ablation (Radiofrequency Ablation (RFA), Microwave Ablation (MWA) and Trans-Arterial Chemo-Embolization (TACE)) are the optimal ways of HCC management. The optimal treatment for HCC has long been debated according to patient condition. Patients and Methods: A retrospective study from January 2012 till March 2019 on 118 patients with HCC (58 patients underwent Hepatic Resection (HR) and 58 patients underwent LDLT). Results: There was no significant difference between the HR group and LDLT group regarding the overall survival and disease-free survival. Overall survival at 1, 3 and 5 yrs. was 94.9%, 78% and 74.5% in LDLT group while was 89.83%, 71.19% and 62.71% in HR group respectively. Disease free survival at 1, 3 and 5yrs. was 88.1%, 62.7% and 61.01% in LDLT group while was 83.05%, 57.63% and 50.85% in HR respectively. Conclusion: In management of early stage HCC HR should be considered an alternative to LDLT. The most important factors affecting HCC recurrence were tumor behavior and preoperative AFP.
   
     
 
       

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