Role of Genetic Polymorphism of Cyp2D6 in Tramadol Related Nephrotoxicity

Faculty Medicine Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Mohammed Zayed Mohammed Hasan
Journal: Journal of Medical Toxicology and Clinical Forensic Medicine Journal of Medical Toxicology and Clinical Forensic Medicine Volume:
Keywords : Role , Genetic Polymorphism , Cyp2D6 , Tramadol Related    
Abstract:
One of the most important tramadol metabolizing enzymes is CYP2D6. The CYP2D6 polymorphism leads to good, poor or no enzyme activity. Genetic testing helps in identification of high risk addicts whom to develop nephrotoxicity as well as management of addicts. The objective of this study is to explore tramadol induced nephrotoxicity associated with CYP2D6 gene polymorphism.
    
     
 
       

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