High efficacy of a characterized lytic bacteriophage in combination with thyme essential oil against multidrug-resistant Staphylococcus aureus in chicken products

Faculty Veterinary Medicine Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Karima Mohammed Issa Abdullah
Journal: Iranian Journal of Veterinary Research Shiraz university Volume:
Keywords : High efficacy , , characterized lytic bacteriophage , combination    
Abstract:
All S. aureus strains were multidrug-resistant (MDR). The isolated phage (vB_SauM_CP9) belonged to the family Myoviridae and maintained its stability at pH (4-9) and temperature (30-70°C). The phage showed lytic activity on ten S. aureus strains and had a burst size (228 PFU/infected cell), latent period (45 min), and rise period (15 min). A combination of S. aureus phage multiplicity of infection (MOI) 10 + thyme oil 1% caused a higher significant reduction in S. aureus growth (87.22%) in artificially inoculated chicken fillets than individual treatment with bacteriophage or thyme essential oil.
    
     
 
       

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