Background: Mitral valve medical procedures have been customarily performed through middle sternotomy. As of late, negligibly intrusive mitral valve medical procedure has acquired endorsement by numerous specialists with leaned toward postoperative results. Patients and Methods: A forthcoming near examination included 46 patients who had mitral valve sickness. The patients were haphazardly doled out into bunch(A)were worked through the less Intrusive right anterolateral thoracotomy approach and gathering (B) Were worked through conventional middle sternotomy approach. All patients were followed up to survey the post operative result of the two methodologies. Results: The last examination remembered 23 patients for each gathering. There was measurably high tremendous contrast with respect to skin cut length (8.2±1.85cm in bunch A and19.66± 2.46cm in bunch B) and all out activity time (173.66±65.99minutes In bunch A and 229.7 ±83.6 minutes in bunch B). There was tremendous distinction(p<0.05) between the two gatherings in the requirement for mechanical ventilation, postoperative blood misfortune and bonding, postoperative torment, emergency clinic stay span and usable expense. Conclusion: Insignificantly obtrusive anterolateral thoracotomy approach for mitral valve medical procedure offers improved results over the customary middle sterontomy approach in regard to cosmoses, postoperative complexities and emergency clinic costs