The present study was conducted to evaluate physicochemical, rheological, microbiological, antioxidant and sensory properties of probiotic fermented camel milk made from camel milk mixed with Oat milk. Fermented camel milk was made from camel milk served as a control, and the other treatments were made from camel milk after mixing with 25 and 50 % Oat milk. Results revealed that mixing of camel's milk with Oat milk were more effective in increasing the total solids, protein, ash, fiber , acidity , viscosity, phenolic content and antioxidant activity and these increments were proportional to the mixing ratio. Fermented camel milk containing 50 % Oat milk had the highest scores for sensory properties compared to other fermented camel milk treatments. This blend (fermented camel milk containing 50 % Oat milk) was evaluated as hypoglycaemic agent streptozotocin-induced diabetic rats. In this respect, twenty four male adult albino rats of Sprague Dawely strain weighing 150- 185 g were divided into 4 groups as follows: Group (1) non-treated non- diabetic rats (negative control). Group (2) diabetic rats (received Streptozotocin (STZ), 60 mg/Kg BW) (positive control).Group (3) diabetic rats fed on basal diet with fermented camel milk (10g/day) by epi gastric tube. Group (4) diabetic rats fed on basal diet with fermented camel milk containing 50 % Oat milk (10g/day) by epi gastric tube. The treatment of diabetic rats with fermented camel milk containing 50 % Oat milk showed a significant decreases(p<0.001) in levels of blood glucose, malondialdehyde (MDA), low density lipoprotein (LDL), cholesterol (CL), triglyceride (TG), AST, ALT , ALP, creatinin and urea and increased (p<0.001) high density lipoprotein (HDL) and total protein and albumin in comparison to diabetic rats. Consumption of fermented camel milk containing 50 % Oat milk in diabetic rat groups caused significant improvement in all these factors, compared to the positive control group (untreated diabetic rats). Also in this study, for the first time, we demonstrated that administration of fermented camel milk containing 50 % Oat milk in diabetic rats resulted in enhanced of blood complications compared to the untreated diabetic group, indicating that fermented camel milk containing 50 % Oat milk can play a preventive role in such patients.