Additive value of 18FDG‑PET/CT to positive 131I whole body scan in recurrent differentiated thyroid cancer patients with potential influence on treatment strategy: single Egyptian center experience

Faculty Medicine Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Heba Mounir AbdelHamid
Journal: Egyptian J of radiology and nuclear medicine Egyptian J of radiology and nuclear medicine Volume:
Keywords : Additive value , 18FDG‑PET/CT , positive 131I whole    
Abstract:
Background: Years ago the utility of of18F-fluorodeoxyglucose-positron emission tomography/computerized tomography (18FDG-PET/CT) in differentiated thyroid cancer was confined mainly to cases with elevated serum thyroglobulin and negative 131I whole body scan. In this study, we try to assess the diagnostic performance of 18FDG-PET/CT in recurrent differentiated thyroid cancer patients with positive 131I whole body scan and in addition to evaluate the impact of 18FDG-PET/CT on the treatment strategy. Results: The 18FDG PET/CT detected tumor recurrence in 35 (81.3%) patients most of them (91.4%) were in stage IV, while the rest 8.5% was in stage III. No recurrence was detected among patients in stage II and III by 18FDG PET/CT. Regarding lesion-based analysis, sensitivity of 18FDG-PET/CT was superior to that of 131I post-therapeutic whole body scan (TxWBS) (78.2% vs. 69.4%, respectively), while both modalities had the same specificity (50%). 18FDG-PET/CT changed the treatment plan in 18 (41.6%) patients. Conclusion: 18FDG-PET/CT may be complementary to 131ITxWBS in high-risk DTC with impact on treatment strategy. Keywords: The 18FDG PET/CT, DTC, 131ITxWBS, Serum Tg, 131I avid
    
     
 
       

Author Related Publications

  • Heba Mounir AbdelHamid, "Comparison of Prostate-specific Membrane Antigen Reporting and Data System Version 1.0 versus 2.0 for Prostate Cancer Assessment", RSNA, 2025 More
  • Heba Mounir AbdelHamid, "Comparative study between 18F FDG-PET/CT and whole body MRI DWIBS in assessment of recurrent breast cancer Indian", .Indian J. Nucl. Me, 2019 More
  • Heba Mounir AbdelHamid, "Radical Conformal Radiotherapy versus Two-Dimensional Radiotherapy in Oligometastatic Breast Cancer Patients:Response, Toxicity, and Survival", Zagazig University medical J, 2020 More
  • Heba Mounir AbdelHamid, "Quantitative scintigraphy in discriminating sacroiliac joint physiological and pathological uptake.", Egyptian J of radiology and nuclear medicine, 2021 More
  • Heba Mounir AbdelHamid, "The utility of technetium-99m pertechnetate thyroid scintigraphy assessing thyroid/salivary ratio as an alternative to thyroid uptake percentage in evaluation of thyroid function, with establishing normal reference values of both parameters: single Egyptian center study", Nuclear medicine communications J, 2022 More

Department Related Publications

  • Rawda Ahmed AbdelHakim AbdulAziz, "Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways", IJMS, 2024 More
  • Mohammed Fathi Ahmed Bayoumi Rmadan, "Dosimetric Comparative Study between Single and Dual Isocenter Stereotactic Body Radiotherapy Plans in Treatment of Multiple Lesions Non-Small Cell Lung Cancer Patients دراسة لمقارنة قياسات الجرعة الأشعاعية بين خطط العلاج الإشعاعي الجسمى المجسم ذو المركز الواحد وذو المراكز المزدوجة في علاج مرضى سرطان الرئة غير صغير الخلايا متعدد البؤر", Iranian Journal of Medical Physics, 2023 More
  • Rehab Hemida Elsayed Muhammad, "The value of fertility-sparing surgery for young females with epithelial ovarian cancer: a comparative study قيمة جراحة الحفاظ على الخصوبة للشابات المصابات بسرطان المبيض: دراسة مقارنة", CURR GYNECOL ONCOL, 2021 More
  • Rehab Hemida Elsayed Muhammad, "Surgical Roles in Management of either Metachronus para-aortic lymph node recurrence or Synchronous paraaortic lymph node metastasis in colorectal cancer patients الأدوار الجراحية في علاج تكرار العقدة الليمفاوية شبه الأبهرية المتزامنة أو الانبثاث المتزامن للعقد الليمفاوية المجاورة للأبهر في مرضى سرطان القولون والمستقيم", Journal of Coloproctology, 2021 More
  • Ahmed Ali Eliwa esmail, "Does a combined CT and MRI protocol enhance the diagnostic efficacy of LI-RADS in the categorization of hepatic observations? A prospective comparative study هل بروتوكول التصوير بالرنين المغناطيسي والتصوير المقطعي مجتمعة تعزز الكفاءة التشخيصية لنظام LI-RADS في تصنيف الملاحظات الكبدية : دراسة مقارنة مستقبلية ؟", European Radiology, 2018 More
Tweet