Parasitic and bacterial infection is common throughout the developing countries of the world. However, housemaids originated from those developing countries are considered a possible source of infection for numerous intestinal parasites as well as other enteropathogenic infections. A total of 100 stool samples were collected from housemaids originated from different countries as Ethiopia, Srilanka, Indonesia and Philippines who visited Hail General Hospital, Saudia Arabia (KSA) during a period from November, 2017 to April, 2018. Each stool sample was examined to detect intestinal parasites using routine parasitological techniques. In addition, standard cultures and biochemical techniques were used for the isolation and identification of pathogenic bacteria. The results revealed that the prevalence rate of intestinal protozoa was 46%. Among those, the infection rates of Giardia lamblia, Cryptosporidium species Entamoeba histolytica and Entamoeba coli were 12%, 10%, 16% and 8 % respectively. Furthermore, four species of helminthes were detected which the infection rates as follows, Ascaris lumbricoides (6%), Entrobius vermicularis (4%), Ancylostoma duodenalis (4%) and Taenia sp. (5%). On the other hand, 49 % of examined housmaids were positive for bacterial pathogens. As the obtained data revealed that Clostridium difficile were the major bacterial pathogen isolated from stool samples (18%) mostly from Srilanka housmaids followed by Enterotoxigenic E.coli (ETEC) (12%) most cases were from Indonesia and Ethiopia. While, the infection rates of Vibrio vulnificus, Bacillus cereus, Campylobacter coli and Aeromonas hydrophila were 10%, 6%, 2% and 1% respectively. The study was the first study highlighting that the intestinal parasitic and bacterial infections are still an important public health problem among housemaids in Northwestern Saudi Arabia. Therefore, more investigations are required to be conducted on a larger scale