Coronavirus disease (COVID-19) is a big problem that scares people all over the world. Life over the world has changed, new aspects for daily life have been introduced. A main problem with COVID-19 is the way it spreads. Covid-19 spreads, primarily, through contact with an infected person when they cough or sneeze, or with an infected surface. Thus, a novel way to make a protection against COVID-19 is to stay away or make yourself isolated from infected people and surfaces. To this end, this work, mainly, aims to design and develop a novel auto-sterilized suit embedded with some medical sensors and other Internet of Things (IoT) devices to provide the required level of isolation, safety, tracking and monitoring of COVID-19 and other pandemic diseases. The developed suit is an auto-sterilized suit for medical purposes and for daily life use. The sterilizing process of the suit is controlled by the IoT paradigm to provide the required control and interface in an automated way. According to the location of the user, wearing the suit, an appropriate sterilizing mode is activated automatically and the suit is sterilized via distributed nozzles over the suit. Furthermore, the distributed medical sensors represent a wireless body area network (WBAN) that is integrated with an IoT gateway to provide periodic measures of medical healthcare parameters such as body temperature, breathing rate, oxygen saturation level and pulse rate. These measures are used to identify the user’s health and the probability of being infected by COVID-19. All measures are transferred to the remote IoT cloud to analyze these data and monitor people around the day. In case of unusual measures, users are moved among three databases associated with health, infected and properly infected users. The suit is under prototyping and the work is mainly introduced to present the design stages.