SPECTROSCOPIC INVESTIGATION OF CHARGE-TRANSFER COMPLEXES OF OXIME INTERMEDIATES PREPARED FROM SOME PHARMACEUTICAL CARBONYL-COMPOUNDS .1.

Spectroscopic studies on the reaction of iodine as delta-acceptor and chloronil as pi-acceptor with oxime intermediates prepared from certain pharmaceutical carbonyl1,4compounds are reported. These compounds include DELTA-3-corticosteroids (prednisone, prednisolone, dexamethasone), DELTA-4-3-ketosteroids (progesterone, testosterone propinate, nandrolone phenpropionate), griseofulvin, carvone, and menthone. The spectroscopic techniques applied are IR, far IR spectroscopy, H-1, C-13-NMR, mass spectra (MS), fast atom bombardment mass spectra (FABMS), electron spin resonance (ESR) and microanalysis of the reaction products. The structure elucidation studies of these complexes confirmed the charge transfer complex (CTC) formation.