STUDIES IN THE FIELD OF HETEROCYCLIC-COMPOUNDS - SYNTHESIS AND BEHAVIOR OF 4-(4-CHLORO-3-METHYL)PHENYL-1-(2H)-PHTHALAZINONE TOWARDS SOME ELECTROPHILES AND NUCLEOPHILES

Faculty Science Year: 1991
Type of Publication: Article Pages: 187-195
Authors:
Journal: REVUE ROUMAINE DE CHIMIE EDITURA ACADEMIEI ROMANE Volume: 36
Research Area: Chemistry ISSN ISI:A1991GR51600022
Keywords : STUDIES , , FIELD , HETEROCYCLIC-COMPOUNDS , SYNTHESIS , BEHAVIOR , 4-(4-CHLORO-3-METHYL)PHENYL-1-(2H)-PHTHALAZINONE    
Abstract:
The phthalazinone derivatives 2a-f have been obtained via the interaction of o-(4-chloro-3-methyl)benzoyl benzoic acid with hydrazine derivatives. The behaviour of 2a towards carbon electrophiles and carbon nucleophiles has been investigated. The chlorophthalazine derivative 3S has been also synthesised from the action of PCl5/POCl3 on 2a. The behaviour of 3S towards nitrogen, and oxygen nucleophiles have been also described.
   
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