Ellagic acid and cilostazol ameliorate amikacin-induced nephrotoxicity in rats by downregulating oxidative stress, inflammation, and apoptosis

Faculty	Medicine	Year:	2022
Type of Publication:	ZU Hosted	Pages:
Authors:	Munira Ismail Alsayd Staff Zu Site Abstract In Staff Site
Journal:	PLoS One Public library of science	Volume:

Keywords :	Ellagic acid , cilostazol ameliorate amikacin-induced nephrotoxicity
Abstract:	Amikacin (AK) has the largest spectrum of aminoglycosides. However, its use is constrained because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants. It has antioxidant, anticarcinogenic, and antimutagen