The protective and therapeutic effects of 5-androstene3β, 17β-diol (ADIOL) in abdominal post-operative adhesions in rat: Suppressing TLR4/NFκB/HMGB1/TGF1 β/α SMA pathway

Faculty Medicine Year: 2022
Type of Publication: ZU Hosted Pages: 7
Authors:
Heba Ahmed Hassan Hanafi
Journal: International Immunopharmacology Elsevier B.V Volume: Volume 109
Keywords : , protective , therapeutic effects , 5-androstene3β, 17β-diol (ADIOL)    
Abstract:
Neurosteroid, 5-androstenediol (ADIOL) had been experimentally applied to protect against many diseases as it had anti-oxidant, anti-inflammatory, and anti-apoptotic effects. In our study, we investigate its role in abdominal postoperative
   
     
 
       

Author Related Publications

  • Heba Ahmed Hassan Hanafi, "Crocin averts functional and structural rat hepatic disturbances induced by copper oxide nanoparticles", Oxford University Press, 2022 More
  • Heba Ahmed Hassan Hanafi, "Comparative effectiveness of methylene blue versus intravenous lipid emulsion in a rodent model of amlodipine toxicity", TAYLOR & FRANCIS LTD, 2019 More
  • Heba Ahmed Hassan Hanafi, "Neuroprotective Effect of ADIOL against Lithium Pilocarpine Induced-Seizures, Behavioral Changes and Cognitive Deficits in Male Mice", . Zagazig University Medical Journal 2019;25(1, 2018 More
  • Heba Ahmed Hassan Hanafi, "Neuroprotective Effect of ADIOL against Lithium Pilocarpine Induced-Seizures, Behavioral Changes and Cognitive Deficits in Male Mice", . Zagazig University Medical Journal 2019;25(1, 2018 More
  • Heba Ahmed Hassan Hanafi, "Repurposing of carvedilol to alleviate bleomycin-induced lung fibrosis in rats: Repressing of TGF-β1/α-SMA/Smad2/3 and STAT3 gene expressions", Elsevier, 2023 More

Department Related Publications

  • Rasha Mohamed Sabry, "Efficacy of olibanum and propolis medicinal extracts versus metronidazole in Giardia lamblia experimentally infected mice", zagazig university, 2020 More
  • Rasha Mohamed Sabry, "Protective Effect of Date Palm Fruits (Phoenix Dactylifera L.) versus Vitamin C Against Mobile Phone Radiation-induced Pituitary Gland Damage in Rats", Zagazig University, 2022 More
  • Rasha Mohamed Sabry, "Mitigation of dexamethasone-induced nephrotoxicity by modulating the activity of adrenergic receptors: Implication of Wnt/β-arrestin2/ β-catenin pathway", elsevier, 2022 More
  • Rasha Mohamed Sabry, "Metabolite Profiling of Date Palm Fruit (Phoenix dactylifera L.) And Its Cytoprotective Effects Versus Vitamin C Against Mobile Phone Radiation-Induced Adrenal Gland Damage In Rats", zagazig university, 2022 More
  • Rasha Mohamed Sabry, "Amlexanox Exhibits Cardioprotective Effects in 5/6 Nephrectomized Rats", -scielo, 2021 More
Tweet