SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME 4-SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINES

Faculty Science Year: 1991
Type of Publication: Article Pages: 26-28
Authors:
ELBAHAIE, S, ELDEEB, A, ASSY, MC
Journal: PHARMAZIE GOVI-VERLAG GMBH Volume: 46
Research Area: Pharmacology \& Pharmacy; Chemistry ISSN ISI:A1991FA20900005
Keywords : SYNTHESIS , BIOLOGICAL-ACTIVITY , SOME 4-SUBSTITUTED PYRIMIDINES , FUSED    
Abstract:
The synthesis of 4-beta-cyanoethylthiopyrimidine 2 and 4-chloropyrimidine 8a was chieved from 4-mercapto-5-acetylpyrimidine (1a). Also the synthesis of thienopyrimidine-7,7-dioxide 6, 4-arylaminopyrimidines 9a-e, 4-alkoxypyrimidines 11a, b, pyrimidoquinazoline 10, thienopyrimidines 19a, b and tetrazolopyrimidine 18 was described.
    
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