Impact ofOmega-3FattyAcidsNano-FormulationonGrowth, Antioxidant Potential,FilletQuality,Immunity, Autophagy-Related Genesand Aeromonashydrophila Resistance inNileTilapia(Oreochromisniloticus)

Faculty Veterinary Medicine Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Asmaa Taha Yassin Ali Feshawy
Journal: antioxidants MDPI Volume: 11
Keywords : Impact ofOmega-3FattyAcidsNano-FormulationonGrowth, Antioxidant Potential,FilletQuality,Immunity, Autophagy-Related Genesand Aeromonashydrophila Resistance inNileTilapia(Oreochromisniloticus)    
Abstract:
In modernaquaculture,enrichingNiletilapia’sdietwithomega-3poly-unsaturatedfatty acids (PUFAs)notonlyplaysanimportantroleinitsgeneralhealthbutalsofortifiesitsfilletwith omega-3-PUFAs.However,themajorchallengeaffectingtheirdeliveryistheirhighinstabilitydueto oxidative deterioration.Thus,theprospectiveincorporationofomega-3-PUFAsintonanocarriers can enhancetheirstabilityandbioactivity.Inthisregard,theeffectofreformulatedomega-3-NPs was investigatedonNiletilapia’sperformance,fleshantioxidantstability,immunity,anddisease resistance.Fourfishgroupssupplementedwithomega-3-PUFAs-loadednanoparticles(omega- 3 NPs)atlevelsof0,1,2,and3g/kgdietandattheendoffeedingtrialfishchallengedwith Aeromonashydrophila. Fishperformance(weightgainandfeedconversion)wasimprovedingroups supplemented withomega-3-NPs(2and3g/kgdiet).Thedepositionofomega-3-PUFAsinfish flesh elevatedwithincreasingdietaryomega-3-NPs.Simultaneouslytheoxidativemarkers(H2O2, MDA, andreactiveoxygenspecies)infishfleshwerereduced,especiallywithhigheromega-3-NPs. Post-challenge, downregulationofIL-1 , IL-6,IL-8,TNF- , andcaspase-1werenoticedafterdietary supplementation ofomega-3-NPs.Moreover,mRNAexpressionofautophagy-relatedgeneswas upregulatedwhilethemTORgenewasdownregulatedwithhigheromega-3NPslevels.Lower expressionof A. hydrophila ahyI andahyRgenesweredetectedwithomega-3NPssupplementation. In conclusion,omega-3-NPsapplicationcanfortifytilapiafleshwithomega-3-PUFAsandaugment its performance,immunity,anddiseaseresistanceagainst Aeromonashydrophila.
    
     
 
       

Author Related Publications

  • Asmaa Taha Yassin Ali Feshawy, "Interactive effects of dietary quercetin nanoparticles on growth, flesh antioxidant capacity and transcription of cytokines and Aeromonas hydrophila quorum sensing orchestrating genes in Nile tilapia (Oreochromis niloticus)", ELSEVIER, 2021 More
  • Asmaa Taha Yassin Ali Feshawy, "Effect of cereal type and plant extract addition on the growth performance, intestinal morphology, caecal microflora, and gut barriers gene expression of broiler chickens", ELSEVIER, 2021 More
  • Asmaa Taha Yassin Ali Feshawy, "Cinnamon Extract and Probiotic Supplementation Alleviate Copper-Induced Nephrotoxicity via Modulating Oxidative Stress, Inflammation, and Apoptosis in Broiler Chickens", MDPI, 2021 More
  • Asmaa Taha Yassin Ali Feshawy, "Cinnamon Extract and Probiotic Supplementation Alleviate Copper-Induced Nephrotoxicity via Modulating Oxidative Stress, Inflammation, and Apoptosis in Broiler Chickens", MDPI, 2021 More
  • Asmaa Taha Yassin Ali Feshawy, "Effect of using pomegranate peel extract as feed additives on performance, serum lipids and immunity of broiler chicks", كلية الطب البيطري, 2013 More

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