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Evolving Fibrinolytic Option in the Management of Second Stage of Empyema. التطورفى خيار مذيبات الفبرين في علاج المرحلة الثانية من الانسكاب البلورى الصديدى.
Faculty
Medicine
Year:
2022
Type of Publication:
ZU Hosted
Pages:
Authors:
Tamer Saliem Mohamed Elawady
Staff Zu Site
Abstract In Staff Site
Journal:
Zagazig University Medical Journal محلي Zagazig University, Faculty of Medicine
Volume:
Keywords :
Evolving Fibrinolytic Option , , Management , Second Stage
Abstract:
Background: Intrapleural fibrinolytics installation is considered an alternative method to aggressive operative intervention. This conservative medical management may decrease morbidity and mortality that were recorded with surgery. Our study investigates the outcome of tissue plasminogen activator (TPA), alteplase, and streptokinase (SK) as a treatment for stage II of empyema. Methods: This study prospectively evaluated 38 patients that had stage II of empyema. The patients were divided into two groups with installing one fibrinolytic protocol into a chest tube for each group: group A, (TPA) and group B, (SK). The evaluation was based upon clinical examination and radiological findings for the efficacy of each protocol. Results: There were no differences in baseline characteristics between both groups. There was a significant improvement after 1st, where 11 patients (52.4%) improved in the TPA group with only 3 patients (17.6%) in the SK group. TPA group showed 100% success, on the other hand, SK Group had 2 patients’ failure (11.8%) and surgical intervention was necessary for them. Hemorrhagic complications were 9.5% and 17.6% for TPA and SK respectively. Finally, there was a significantly prolonged duration of mean hospital stay with SK therapy (5.48 vs 8.59 days). Conclusions: Both fibrinolytic protocols were effective and safe for empyema management, but Alteplase had a better outcome. Keywords: Empyema; Fibrinolytic therapy; Intra-pleural installation; Tissue plasminogen activator; Streptokinase
Author Related Publications
Tamer Saliem Mohamed Elawady, "Early and Late Management of Non-penetrating Traumatic Thoracic Tracheobronchial Injuries. التدبير العلاجى المبكر والمتأخر لإصابات القصبة والشعب الهوائية الصدرية غير المخترقة", محلي Al-Azhar University (Assiut Branch), 2013
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Tamer Saliem Mohamed Elawady, "A - 13 Years of Single-Center Experience in the Management and Outcome of Esophageal Perforation. ثلاثة عشر عامًا من الخبرة في مركز واحد في التدبير العلاجى ونتائج انثقاب المريء.", محلي Zagazig University, Faculty of Medicine, 2022
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Tamer Saliem Mohamed Elawady, "Aortic Prosthesis - Patient Mismatch as a Risk Factor on Regression of Left Ventricular Mass. عدم تطابق الصمام الأورطى الاصطناعى مع المريض كعامل خطر على تراجع كتلة البطين الأيسر.", محلي Zagazig University, Faculty of Medicine, 2022
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Tamer Saliem Mohamed Elawady, "Is right lateral mini-thoracotomy preferable to intermediate sternotomy in mitral valve surgery? هل يُفضل شق الصدر الجانبي الأيمن الصغير على شق القص المتوسط في جراحة الصمام الميترالي؟", محلي Zagazig University, Faculty of Medicine, 2022
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Tamer Saliem Mohamed Elawady, "Pleurodesis Using Bleomycin Ampoules, Doxycycline Capsules, and Povidone Iodine Solution in Patients with Malignant Pleural Effusion in Zagazig University Hospitals. التصاق الجنب باستخدام أمبولات بلوميسين وكبسولات دوكسيسيكلين ومحلول بوفيدون اليود في مرضى الانصباب الجنبي الخبيث في مستشفيات جامعة الزقازيق.", محلي Zagazig University, Faculty of Medicine, 2022
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Mohamed Mamdouh Abdalraouf ElShaarawy, "16- Endoventricular plasty in management of left ventricular aneurysm", لايوجد, 1900
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Mohamed Mamdouh Abdalraouf ElShaarawy, "25- Total mitral valve reservation in mitral replacement for mitral regurgitation.", لايوجد, 1900
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