Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Effect of parsley essential oil on digestive enzymes, intestinal morphometry, blood chemistry and stress-related genes in liver of Nile tilapia fish exposed to Bifenthrin
Faculty
Veterinary Medicine
Year:
2022
Type of Publication:
ZU Hosted
Pages:
Authors:
Mayada Ragab Farag Awadallah
Staff Zu Site
Abstract In Staff Site
Journal:
Aquaculture Elsevier
Volume:
Keywords :
Effect , parsley essential , , digestive enzymes, intestinal
Abstract:
Bifenthrin (BF), third-generation synthetic pyrethroids (SPs), is extensively used as an insecticide for its higher killing activity, upgraded stability, and lower mammalians toxicity, compared to earlier SPs. The monitoring of high concentrations of BF in aquatic environment addresses a significant concern to aquatics including fish. In the current investigation, O. niloticus fish was subjected to bifenthrin insecticide (BF) at a dose level equal to 1/10 LC50 (0.68 μg/L) for a period of successive 60 days, followed by assessing of BF-induced hepatotoxic and digestive insults through the biochemical and transcriptomic changes. Moreover, the efficiency of parsley (Petroselinum crispum) essential oil (PLO) in two dose levels to mitigate these impacts was evaluated. Our findings showed that BF induced a high rate of mortality and altered the total body composition, serum biomarkers of hepatorenal function and liver glycogen. Intestinal morphological changes were recorded as well as suppression of activity of the intestinal α-amylase, lipase and protease. Oxidative injury was asserted by the recorded elevation of hepatic malondialdehyde (MDA), protein carbonyl, accompanied with depletion of the content of GSH, and repression of the activity of the both antioxidant enzymes (SOD and CAT). In addition, the RT-PCR analysis of stress-mediated genes showed an upregulated expression manner of tumor suppressor protein (P53), Caspase-3, and heat shock protein-70 (HSP-70) in hepatic tissue. Concurrent supplementation of PLO at the both levels in the diet with BF intoxication modulated the recorded deleterious influences in a dose- dependent way. The data from the current study stated the induction of hepatotoxicity and digestive disorders due to BF exposure in O. niloticus fish, and approved the protective efficacy of PLO to be a promising additive to fish feed
Author Related Publications
Mayada Ragab Farag Awadallah, "Ameliorative impact of taurine on oxidative damage induced by Ipomoea carnea toxicity in wistar male rats through modulation of oxidative stress markers, apoptotic and Nrf2 pathway", Elsevier, 2021
More
Mayada Ragab Farag Awadallah, "A comprehensive review on the health benefits and nutritional significance of fucoidan polysaccharide derived from brown seaweeds in human, animals and aquatic organisms", Wiley, 2021
More
Mayada Ragab Farag Awadallah, "Palliative Effects of Spirulina platensis Against Cadmium Induced Hepaotoxicity in Albinob Rats", Faculty of Veterinary Medicine, 2015
More
Mayada Ragab Farag Awadallah, "Differential susceptibility of kidneys and livers to proliferative processes and transcriptional level of the genes encoding desmin, vimentin, connexin 43, and nestin in rats exposed to furan", elseiver, 2018
More
Mayada Ragab Farag Awadallah, "Evaluating the ameliorative efficacy of Spirulina platensis on spermatogenesis and steroidogenesis in cadmium-intoxicated rats", springer, 2016
More
Department Related Publications
Ahmed Mohamed Elsayed Ahmed Omer , "The cartilages of the external ear of one-humped camel ( Camelus dromedarius). ", لايوجد, 1900
More
Ahmed Mohamed Elsayed Ahmed Omer , "Photochemical deleterious effects of the visible light on the visual pathway of guinea pig: Cytoarchitectural and Histochemical studies. ", لايوجد, 1900
More
Ibrahiem Mohamed Salem khedr, "Cartilagines laryngis of the Buffalo in Egypt (Bos bubalis 1,.). ", لايوجد, 1900
More
Ibrahiem Mohamed Salem khedr, ". Some anatomical aspects of the extrensic intiscies of tongue of the one-humped camel (Camelus dromedarius). ", لايوجد, 1900
More
Ibrahiem Mohamed Salem khedr, "Morphological studies on the os hyoideum of the Butffalo(.( Bos btbalis L ). ", لايوجد, 1900
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف