Background: Autism spectrum disorder (ASD) sufferers are now thought to be at the extreme end of a continuum of autistic-related social, communicative, and behavioural traits that have been found to be more pronounced, even though they fall below the clinical threshold, in their relatives and to be normally distributed in the general population .Aim: Detection of autistic traits among different college students as well as its relation to their academic performance, which will be reflected on their achievement in case of proper and early management. Methods: 4000 students from practical and theoretical faculties applied Autism spectrum quotient Questionnaire. Results: There is statistically significant difference in degree of autistic traits as regard type of college. Practical students represent the majority of sample in group A (group with low total AQ score), while theoretical students scored the majority of the sample in groups B (groups with high total AQ score).There is also statistically significant difference in degree of autistic traits as regard academic achievement. About 65.4% of students of group A (low AQ score) scored excellent, while 41.2% of students in group B (high AQ score) scored excellent. Conclusion: Autistic traits are distributed among general college students in various degrees and are higher in theoretical students than practical students. Female gender was found to be significantly related to low AQ scores.