Vitamin D receptor gene FokI polymorphism in Egyptian children and adolescents with SLE: A case-control study

Faculty Medicine Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Atef Mohamed Mohamed Khaliel
Journal: Pediatric Lupus Pediatric Lupus Volume:
Keywords : Vitamin , receptor gene FokI polymorphism , Egyptian    
Abstract:
: Childhood-onset systemic lupus erythematosus (cSLE) is a lifelong autoimmune disorder. The vitamin D receptor (VDR) gene is a potential candidate gene for cSLE susceptibility. In this study, we aimed to investigate the FokI polymorphism in the VDR gene in Egyptian children and adolescents with SLE, to determine whether this polymorphism could be a genetic marker for cSLE susceptibility or disease activity and we also measured the serum level of 25-hydroxyvitamin D [25(OH) D] to assess its relation to such polymorphism
    
     
 
       

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