Background: Diseases related to the thyroid gland are one of the greatest often seen endocrine diseases across the world. Total thyroidectomy is presently the favoured treatment for several thyroid disorders. The aim of study aimed to assess effect of neck stretching exercises on patients’ neck disability and pain after thyroidectomy. Design: This study used quasi experimental design. Setting: the study was performed at Zagazig university hospital’s general surgery ward and outpatient surgery clinic. Subjects: Participants were randomly assigned to one group: stretching exercise (n= 38) or control exercise (n= 38). Tools: Three methods were implemented: 1) a Patient assessment sheet, 2) a visual analogue scale for pain, and 3) an index of neck disability. Results: Both groups had significant differences in neck’s disability and pain after 7- and 30-days following thyroidectomy. Conclusion: Neck stretching exercise was effective in diminishing the patient’s neck disability and pain following thyroidectomy. Recommendation: Conducting further studies on extra samples from participants in several hospitals in various governorates are recommended.