This paper aims to propose a systematic approach to identify, analyze, and respond to the risks of climate change on irrigation water in arid regions using the Risk Management process. The compound efect of these risks was analysed using Monte Carlo Simulation, which indicated a 69% loss in crop production due to climate change at a 90% confdence level. The proposed responses to the risks of climate change include strategies to avoid, transfer, mitigate, and/or accept these risks. The study has made three contributions to the state of the art. First, to adopt a wellrecognized risk management methodology in climate change studies. Second, to quantify the compound efect of climate change risks on irrigation water in arid regions. Third, to recommend a set of response strategies to help policymakers mitigate the inevitable harmful efect of climate change on irrigation water.