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MRI as a road map for surgical Intervention of acute invasive fungal sinusitis in Covid-19 era التصويربالرنين المغناطيسي كخريطة طريق للتدخل الجراحي لإلتهابات الجيوب الأنفية الفطرية الغازية الحادة
Faculty
Medicine
Year:
2022
Type of Publication:
ZU Hosted
Pages:
Authors:
Mohamed Hassan Mohamed Isa
Staff Zu Site
Abstract In Staff Site
Journal:
Clinical Otolaryngology Clinical Otolaryngology
Volume:
Keywords :
, , , road , , surgical Intervention , acute invasive fungal
Abstract:
Acute invasive fungal sinusitis (AIFS) is a rare disease affecting immunocompromised patients with high mortality rate (50%–80%).1 AIFS is usually due to Aspergillus or Zygomycetes species. These fungal spores are inhaled and germinated within the nose and paranasal sinuses; then fungal hyphae invade submucosal blood vessels leading to vasculitis and tissue necrosis. Either direct or vascular extension may occur leading to advanced condition (rhino-orbito-cerebral mucor mycosis).2 In Covid-19 era, incidence of AIFS has increased without explanation, may be due to immunosuppressed state, high ferritin level associated with SARS-CoV-2, and prolonged hospitalisation with excessive steroid and oxygen therapy utilisation; in addition to standard risk factors for AIFS.3 Any refractory sinus manifestation with orbital complications (visual defect, proptosis and ophthalmoplegia) should be investigated for possibility of AFIS especially in high risk patients by nasal endoscopy, radiology and biopsy.4 Early diagnosis and management are the key consideration to minimise mortality rate. Mortality rate discrepancy in between studies may be due to different variables as reversibility of immunocompromised state, virulence of fungi, stage of invasive fungal infection, compliance with antifungal medications and surgical debridement (when to interfere, debridement efficacy).4,5 In this study, MRI findings in AIFS patients, recently recovered from Covid-19, were assessed and correlated with intraoperative findings to evaluate predictability of MRI for severely fungal affected tissues beyond scope of ordinary endoscopic sinu7s surgery.
Author Related Publications
Mohamed Hassan Mohamed Isa, "Swallowing outcome after TORS for sleep apnea: short- and long-term evaluation", springer link, 2015
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Mohamed Hassan Mohamed Isa, "Olfactory Bulb Volume Changes in Patients with Sinonasal Polyposis A Magnetic Resonance Imaging Study", SAGE journals, 2012
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Mohamed Hassan Mohamed Isa, "Barbed reposition pharyngoplasty (BRP) for OSAHS: a feasibility, safety, efficacy and teachability pilot study. “We are on the giant’s shoulders”", springer link, 2015
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Mohamed Hassan Mohamed Isa, "Powered intracapsular tonsillotomy vs. conventional extracapsular tonsillectomy for pediatric OSA: A retrospective study about efficacy, complications and quality of life", elsevier, 2015
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Mohamed Hassan Mohamed Isa, "Tips and Tricks in Transoral Robotic Surgery for Challenging Vascular Tumors", wolters kluwer, 2015
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Department Related Publications
Ismaeil Sedik Hassan Elnashar, "Anatomical study:Endoscopic anterior skull base resection", egyptian j of neurosurgery, 2010
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Wael Fayez Nasr, "Laryngeal ultrasound as effective as CT scans for the diagnosis of various laryngeal lesions", The Egyptian Oto - Rhino - Laryngological Society, 2013
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Ibtesam Hamed Abdelmegeed, "Noise Induced Hearing Loss (NIHL) Among Workers in Textile Factory", Egypt, 2014
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AbdelZahir Elsayed Tantawi Mohammad, "مقارنة بين استعداد الحساسية فى الجهاز التنفسى العلوى وبين الربو الشعبى بواسطة جلوبين المناعة اى فى البلازما والافرازات", المجلة الطبية جامعة الزقازيق, 1984
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Wael Fayez Nasr, "Which Is Preferable As Hypotensive Agent: Labetalol Or Nitroglycerin In Functional Endoscopic Sinus Surgery Operations In Adults", elazhar university, 2010
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