The research aims to study the effect of a plyometric program with and without blood flow restriction on some physical variables and the effectiveness of shooting for basketball players, by identifying: • The effect of a plyometric program with blood flow restriction on some physical and skill variables under study for basketball players (the experimental group). • The effect of a plyometric program without blood flow restriction on some physical and skill variables under study for basketball players (the control group). • Significance of differences between the experimental and control research groups (plyometric training with blood flow restriction - plyometric training without blood flow restriction) in some physical and skill variables under study. The researchers used the experimental approach due to its suitability to the type and nature of this research, through the experimental design, the experimental group (plyometric training with blood flow restriction) and the control group (plyometric training without blood flow restriction), using the pre and post measurements, in order to identify the effect of the training program. The research community represents the players of basketball clubs under (20) years old in Sharkia Governorate, their number is (5) clubs, and their number is (94) players, who are registered in the records of the Egyptian Basketball Association for the 2018/2019 season. The researchers recommend the following: • The use of plyometric training with blood flow restriction in the development of muscular strength, speed and skill variables associated with various sports activities. • Using research variables used in different specialized activities with the use of the KAATSU Nano device to restrict blood flow. • The use of the low-intensity training program with blood flow restriction to develop the variables of muscular strength, speed, and related skill variables. • Using the tests used in the research and applying them to different samples and different activities. • The use of blood flow restriction training as a modern training trend in the development of muscular strength, speed and associated skill variables.