This research aimed to identify the effect of using the "Insanity" training program on some physical variables and offensive and defensive skills of the handball player. The researcher used the experimental approach, using the design of the pre and post measurements of an experimental group. The sample included (14) in the elite club in the city of Tenth of Ramadan and registered in the Egyptian Handball Federation. The most important results were: The effect of the training program using human training "Insanity" positively on the development of the physical variables under consideration, where the improvement in the transition speed was 15.09%, and the improvement in the muscle strength variable ranged between (10.48%: 13.30%) and the improvement rate ranged In the variable force marked with speed for the muscles of the legs and arms between (12.68%: 17.28%), the improvement rate in the fitness variable was 7.43%, and the percentage of improvement in the muscle endurance variable reached 16.68% for the individuals in the sample being examined. And the effect of the training program using the human training "Insanity" positively on the development of the skill variables under discussion, where the improvement in passing and receiving ranged between (10.80%: 14.88%), and the improvement rate in the shooting aiming variable was 16.51% and the improvement rate of the defensive movement variable reached 21.32% The rate of improvement in the wall block variable was 4028% for the individuals in the sample in question