Background: The coronavirus (COVID-19) global pandemic negatively affected people’s way of life regardless of age, sex, or ethnicity. This infectious disease is particularly lethal among the elderly, with even higher fatality rates among this age group. Aim of the study: Assess knowledge and quality of life of rural older adults during COVID-19 pandemic. Subjects and Methods: Research design: A descriptive design was utilized. Setting: The study was conducted in a rural area Shobra el nakhla selected randomly from Sharkia Governorate, Egypt. Subjects: Purposive sample composed of 300 older adults aged ≥60 years. Tools of data collection: Three tools were used to collect the study data. Tool I: A structured interview sheet. Tool II: knowledge of the studied older adults about Covid-19. Tool III: WHO Quality of life instrument short form (THE WHOQOL-BREF). Results: among the studied older adults, 68.7% had inadequate knowledge and 51.3% had poor quality of life. Statistically significant relations were found between quality of life and illiteracy, insufficient monthly income, and unmarried status. Conclusion: two-third of older adults had inadequate knowledge and more than half of studied older adults had poor quality of life during covid-19 pandemic. Recommendation: Healthcare Providers should be aware that older individuals were particularly vulnerable to the effects of covid-19 on quality of life and explore strategies to minimize their suffering during the COVID-19 pandemic. Keywords Covid-19, older adults, quality of life, rural area