Study’s purpose: to assess health literacy, protective measures among older adults and the association between them. Methodology: a descriptive study conducted in a rural area at Sharkia Governorate, Shobera el nakhla with a random sample composed of 300 older adults. Health literacy was measured by the European health literacy survey questionnaire (HLS-EU-Q) and protective measures were measured by a tool developed by the researchers. Association between health literacy and protective measures was identified through Pearson’s correlation coefficient. Major results: 44.3% and 24.3% of older adults had inadequate and problematic health literacy, respectively and 58.0% of them had unsatisfactory protective measures. Highly Statistically significant positive correlation wasfound between health literacy and protective measures p < 0.01. Clinical implications: Better health literacy means recognizing how to protect oneself and others through basic measures. We should invest in strategies to increase health literacy so that older adults’ practices improve and coronavirus transmission is reduced.