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Impact of bariatric surgery on androgen profile and ovarian volume in obese polycystic ovary syndrome patients with infertility
Faculty
Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Wael Mahmoud Ibrahim Abdullah
Staff Zu Site
Abstract In Staff Site
Journal:
Saudi Journal of Biological Sciences elsevier
Volume:
Keywords :
Impact , bariatric surgery , androgen profile , ovarian
Abstract:
Obesity has major adverse effects on reproductive performance and fertility potential especially in women with polycystic ovary syndrome. In this study, we aimed to evaluate the consequences of excess weight reduction by bariatric surgery on androgen levels, and ovarian volume by ultrasonography in obese polycystic ovary patients. This one year Cohort study was carried out in Zagazig university hospitals. The study included 36 infertile women with PCOS and obesity, who underwent bariatric surgery (sleeve gastrectomy or gastric bypass). Patients were evaluated for free and total serum testosterone levels, Sex hormone binding globulin (SHBG), free androgen index (FAI) and also ovarian volume by ultrasound pre-operatively, 6 months and 1 year after surgery. The results showed significant reduction in Body Mass Index, free and total serum testosterone levels and rise in SHBG and regulation of menstrual cycle at 6 and 12 months after operation. Free androgen index and ovarian volume by ultrasound also significantly decreased (p < 0.001) .As a conclusion, Bariatric surgery results in durable loss of weight and restores the normal physiological balance of androgenic milieu and ovarian morphology by ultrasound, in infertile women who have Polycystic ovary syndrome.
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Wael Mahmoud Ibrahim Abdullah, "Laparoscopic sleeve gastrectomy with loop bipartition versus laparoscopic sleeve gastrectomy in treating obese people with type II diabetes mellitus: a prospective randomized comparative study", The egyptian society of surgeons, 2019
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Department Related Publications
Ahmed Alsayed Ahmed Lashen, "تصليح الفتق الاربى " محاولة اليجاد طريقة جديدة", لايوجد, 1900
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Ahmed Mosaad Ibrahiem Nagieb, "افرازات حلمة الثدي اهمية العينة الجرالحية لحالات افرازات حلمة الثدي ذات القيمة الجراحية", لايوجد, 1900
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Ahmed Mosaad Ibrahiem Nagieb, "استئصال القناه الابنه بسبب افراز من قناة بجملة الثدي باستعمال طريقة جراحية جديدة لتحديد بواسطة الحقن وعادة افيدون ", لايوجد, 1900
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