This study aimed to investigate the impact of CEO power on agency costs in the Egyptian listed companies, especially in light of the scarcity of previous studies that have been subjected to study this impact in the Egyptian environment. To achieve this goal, the researcher has built a composite index to measure CEO power consists of four mechanisms, namely: 1) CEO duality, 2) CEO tenure, 3) CEO ownership, and 4) board independence. In order to test the hypotheses, the researcher relied on a sample of 100 listed non-financial Egyptian companies, with 400 firm-year observations, between 2013 and 2016. After controlling the effects of board size, firm size, dividend payout, growth opportunities, and financial leverage on agency costs of the Egyptian listed companies, the researcher find by using multiple linear regression analysis, a positive association between CEO power and agency costs. Regarding the impact of the four mechanisms that make up the power index on agency costs, the results showed a positive association between CEO duality, CEO tenure, the presence of a majority of the non-executive directors on the board and agency costs. While the results showed no significant relationship between CEO ownership and agency costs.