This study aimed to investigate the effect of managerial entrenchment mechanisms on the value of Egyptian listed companies. This study examines the potential impact of five mechanisms of managerial entrenchment on the value of Egyptian listed companies. These mechanisms include: CEO duality, CEO tenure, board independence, managerial ownership, and financial leverage. In order to test the hypotheses, we relied on a sample of 101 listed non-financial Egyptian companies, with 606 firm-year observations, between 2010 and 2015. The study used two indicators to measure the firm’s value: Tobin’s Q ratio, and industry-adjusted Tobin’s Q ratio. After controlling the effects of firm size, profitability, board size, and institutional ownership, we find by using multiple linear regression analysis, a negative association between CEO duality, the percentage of non-executive directors on corporate board of directors and firm value. We also find a positive association between managerial ownership, financial leverage and firm value. We failed to reach any significant impact for CEO tenure on firm value.