A Various of studies investigate the determinants of the relevance of accounting information for decision making. The current research uses ohlson (1995) model to evaluate and measure the value relevance of accounting information in the Egyptian market. Also, the research aims to test the quality of external audit that measured by the size of audit office and industrial specialization as one determinant of value relevance of accounting information. The current research uses two models that depend on stocks prices and returns. From 200 – 2019, a sample of 60 companies is selected. Affixed effect model is used to test research models. Using R2 measure, the results indicate that the explanatory power of two (or both) models is increasing after adding audit quality which means that the value relevance of accounting information is improved after adding this variable. In addition, the results indicate that the interaction of industrial specialization with book value and stock profit or (earnings) in two models is significant which indicate that industrial specialization affect the value relevance of stock book value and profit (or earnings). Finally, the interaction of the size of audit office is significant which means that the office size do not affect the value relevance of accounting information. These results indicate that the study of variables individually is considered as an important for explanation which consistent with statistical results that indicate there is value relevance of stock book value mainly not interacts only for both models.