Serum Procalcitonin as A Diagnostic and Prognostic Marker for Bacterial Community - Acquired Pneumonia

Faculty Medicine Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Egyptian Journal of Immunology Egyptian Journal of Immunology Volume:
Keywords : Serum Procalcitonin , , Diagnostic , Prognostic Marker , Bacterial Community    
Abstract:
For community acquired pneumonia (CAP), the discrimination between typical and atypical bacterial causes could influence antibiotic choice and outcome of patients. Objective of this study was to evaluate the utility of serum procalcitonin (PCT) level as a diagnostic and prognostic marker for CAP. Typical bacteria were isolated and identified by conventional methods. An indirect immunoflourescence assay was used to diagnose atypical bacteria. Serum level of PCT was measured by ELISA and clinical outcome was evaluated. Out of 240 enrolled CAP patients, 95 (39.6%) had bacterial etiology (30.8 % typical bacterial pneumonia and 8.8% atypical pneumonia). Ninety five bacterial CAP patients were divided into 3 groups; group 1 (mortality, 20.1%), group 2 (complications, 52.6 %) and group 3 (discharge, 26.3 %). Group 1 patients had the highest PCT level in serum compared to other groups with a statistically significant difference (P˂ 0.001). A statistically significant higher serum level of PCT was detected in typical than atypical pneumonia (P˂ 0.001). In conclusion, serum PCT level may serve as a diagnostic and prognostic marker in CAP.
   
     
 
       

Author Related Publications

  • Heba Abdel- Aziz Mohammed Abedulaziz, "Detection of toxin- antitoxin system in Acinetobacter baumannii isolated from patients at Zagazig University Hospitals.", Egyptian Journal of Medical Microbiology, 2018 More
  • Heba Abdel- Aziz Mohammed Abedulaziz, "Anti-Helicobacter pylori activity of Egyptian medicinal plants and bacteriophages", Microbes and Infectious Diseases, 2021 More
  • Heba Abdel- Aziz Mohammed Abedulaziz, "Biocidal Efficacy Study of Nonthermal Plasma on Microbial Planktonic and Biofilm Forms", جامعة القاهرة, 2016 More
  • Heba Abdel- Aziz Mohammed Abedulaziz, "Diagnostic performance of direct latex agglutination, post-enrichment latex agglutination and culture methods in screening of group B streptococci in late pregnancy: a comparative study", Dove Medical Press Ltd, 2019 More

Department Related Publications

  • Doaa Alhussein Mostafa Abo-alella, "Association of Serum IL 6 with Different Clinical Presentations of Systemic Sclerosis Patients: A Case-Control Study", Zagazig University; Faculty of Medicine, 2021 More
  • Rania Mohamed Mohamed Ebrahiem, "Prevalence and antimicrobial resistance patterns of nosocomial pathogens causing surgical site infections in an Egyptian university hospital", Medical Microbiology & Immunology Department, Faculty of Medicine, Zagazig University, 2020 More
  • Rehab Hosny Mohamed Abedallah, "Sero-prevalence of anti-SARS-CoV-2 antibodies among healthcare workers: A multicenter study from Egypt.", elsevier, 2021 More
  • Lubna Abdel- Aziz AbdelAzim, "Sero-prevalence of anti-SARS-CoV-2 antibodies among healthcare workers: A multicenter study from Egypt.", elsevier, 2021 More
  • Ghada Mohamed Samir, "Increased serum APRIL differentially correlates with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients.", RheumatolInt, 2014 More
Tweet