Vegetable and fruit peels are commonly rich in phenolic with antioxidant properties so it considered metabolic syndrome remedies. This study was evaluated the phenolic compounds of peas and tangerine peels powder may as beneficial health on diabetic rats were fed on crackers enrich with 10% from its. The chemical composition of crackers was determined. Thirty healthy adult male albino rats were separated into five groups (six rats each) as follows: Group (1) were fed on basal diet as negative control. Other groups were injected subcutaneous with Alloxan (150 mg/kg body weight) to induce diabetes. Group (2), received the normal diet as a positive control, Group (3) intake standard diet and crackers without peels. Groups (4 and 5) fed on natural diet and cracker with 10% peas and tangerine peels respectively for 8 weeks. In addition, glucose, lipid profile, liver and kidney functions were determined in serum and examination tissues were carried out. Results obtained that tangerine peels had the highest antioxidant activity and phenolic compounds. Pea’s peels were the highest value of protein and fiber while fat and moisture contents is the lowest. Enrichment of crackers with 10% tangerine and pea’s peels caused increases in sensory evaluation. Cracker with tangerine and peas peels showed improve glucose, serum lipid profile, liver, kidney functions. Pancreas tissues of groups (4, 5) were ameliorate compare with group (3). Thus, the study imagery those crackers containing 10% peas and tangerine peels exhibit high potential to enhance the nutritional value and protection against diabetes diseases.