Segregated responses of mammary gland development and vaginal opening to prepubertal genistein exposure in Bscl2−/− female mice with lipodystrophy

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Ezat Mahmoud Mohamed El Zowalaty
Journal: Reproductive Toxicology Elsevier Volume:
Keywords : Segregated responses , mammary gland development , vaginal    
Abstract:
• Accelerated pubertal mammary gland ductal development in Bscl2−/− mice. • Delayed vaginal opening in Bscl2−/− mice. • Accelerated pubertal onset by postweaning dietary genistein exposure. • Segregated responses of mammary gland development and vaginal opening to prepubertal genistein exposure in Bscl2−/− mice. • Decreased ERβ expression in Bscl2−/− mammary gland ductal epithelium.
    
     
 
       

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