Tin ore plays a vital role in several industries. Tin ore could contain natural radioactive nuclides of 238U, 232Th, and 40K with various concentrations which might be caused a significant exposure radiation levels to the workers who handle the Tin ore in the factory. Thus, the evaluation of natural radioactive nuclides 238U, 232Th, and 40K in the Tin ore is important from the point of view of radiation protection to save the workers from the radiation hazards. Approach: The natural radionuclides of 238U, 232Th, and their daughters and 40K as well in Tin ore were measured using in gamma-ray spectrometry system. The results: The activity concentrations of 238U, 232Th, and 40K in Tin ore was 42.77, 21.9 and 145.33Bq kg-1, respectively. Conclusion: The natural radionuclides concentrations in Tin ore were lowered the exemption level recommended by IAEA. Moreover, all the radiological hazard indices were very low compared with the safe values recommended with UNSCEAR. Therefore, the obtained results imply that Tin ore can be used in industries with any risk of radiation.