The research aims to develop higher order thinking skills and the enjoyment of learning among middle school students through a proposed program based on next generation science standards (NGSS), The researcher prepared research materials and tools represented in the proposed program in the field of earth and space sciences entitled "Earth systems and human activities" and a teacher's guide to explain how to teach the program, test higher order thinking skills, and measure learning enjoyment in science, The experimental approach was used for the quasi-experimental design with one experimental group, and the research was applied to a group of second-grade preparatory students at Al-Aslouji Joint Preparatory School, Zagazig Center, Sharkia Governorate, and the number was 42 pupils, The following results were reached: 1- There are statistically significant differences between the mean scores of students in the pre and post applications to test higher order thinking skills in the sciences as a whole and in its sub-skills separately. 2- There are statistically significant differences between the mean scores of students in the pre and post applications of the learning enjoyment scale in the sciences as a whole and in its sub-dimensions separately. Keywords: proposed program based on next generation science standards NGSS, higher order thinking skills, learning enjoyment in science.