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Gastrointestinal Basidiobolomycosis: An Emerging, and A Confusing, Disease in Children (A Multicenter Experience)
Faculty
Medicine
Year:
2018
Type of Publication:
ZU Hosted
Pages:
194-199
Authors:
Maysa Abdullah Saeed Muhmd
Staff Zu Site
Abstract In Staff Site
Journal:
.Eur J Pediat Surg Thiem Medical Publishers Inc.
Volume:
Keywords :
Gastrointestinal Basidiobolomycosis: , Emerging, , , Confusing, Disease , Children
Abstract:
Introduction: Gastrointestinal basidiobolomycosis (GIB) is an emerging fungal infection in children that leads to diagnostic confusion. Aim: Our study aim was twofold: a systematic review of published literature and an update of some Saudi Arabia hospital series to analyze their as well as our own experience in diagnosis and management of GIB. Material and methods: This clinical study included 18 children whose final diagnosis was GIB. The patients, who ranged in age from 5 to 10 years, were admitted between November 2009 and November 2015 with vague abdominal pains with or without abdominal masses for further investigation. Results: Abdominal pain was the most common presenting symptom (94.4%) followed by constipation and abdominal mass (83.3 and 77.8%, respectively); fever was present in only 22.2% of the cases. Elevated inflammatory markers and eosinophilia (94.4%) appeared as prominent laboratory findings. Conclusion: We conclude that diagnosing GIB in children requires a high index of suspicion, awareness, and consideration of its possibility in the differential diagnosis in patients with abdominal masses and eosinophilia, particularly in areas where it is endemic. Increased awareness of this clinical entity, early surgical resection of the infected tissue, and prolonged treatment with itraconazole offer the best chance for curing the disease.
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Department Related Publications
Ahmed Mohamed Mahmoud ebrahym, "مدى انتشار الأجسام المناعية لفيرس نقص المناعه فى الانسان والمستضد السطحى لفيرو الإلتهاتب الكبدى ب ، والجسام المناعية لفيروس الإلتهاب الكبدى ج بين المتبرعين بالدم بحافظة الشرقيه :", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, " التشخيص المناعى للإصابة بطفيل الجارديا عن طريق اكتشاف مستضدات الجيارديا . ", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "دراسة بكتيرية باثولوجية للعمدة فى حالات تضخم الكبد والطحال المتوطن ", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "الكبد والطحال دراسة بكتيرية باثولوجية للمعدة فى حالات تضخم المتوطن", لايوجد, 1900
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Ahmed Mohamed Mahmoud ebrahym, "مصاحبه فيروس الالتهاب الكبدى ( ج ) وتضخم الكبد والطحال المتوطن", لايوجد, 1900
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