Molecular characterization and analysis of the association of growth hormone 1 gene with growth traits in Chinese indigenous yak

Faculty Agriculture Year: 2021
Type of Publication: ZU Hosted Pages:
Authors:
Sameh Abdelbary Abdelnour abdelbary
Journal: Tropical Animal Health and Production ٍSpringer Volume:
Keywords : Molecular characterization , analysis , , association , growth hormone    
Abstract:
This study aimed to investigate the effects of polymorphisms in growth hormone 1 (GH1) gene on the growth traits in Chinese indigenous yak. Using the polymerase chain reaction-restriction fragment length polymorphism (PCR-PFLP) approach, one novel single-nucleotide polymorphism (SNP), termed as g.1721G>A, was identified in the exon 4 of GH1 gene in 423 individuals of yak population. Based on the chi-square (χ2) test, the frequencies of g.1721G>A alleles agreed with Hardy-Weinberg equilibrium (HWE) (P < 0.05). A significant association was observed between this SNP and several growth traits (P < 0.01 or P < 0.05), in which the genotype GG exhibited the best values. The present study suggested that the identified SNP was a useful genetic marker for the improvement of growth traits in Chinese indigenous yak.
    
     
 
       

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