MRI as a road map for surgical intervention of acute invasive fungal sinusitis in Covid-19 era

Faculty	Medicine	Year:	2021
Type of Publication:	ZU Hosted	Pages:
Authors:	Staff Zu Site Abstract In Staff Site
Journal:	Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-rhino-laryngology & Cervico-facial Surgery Wiley Online Library	Volume:

Keywords :	, , , road , , surgical intervention , acute invasive fungal
Abstract:	Acute invasive fungal sinusitis (AIFS) is a rare disease affecting immunocompromised patients with high mortality rate (50%–80%).1 AIFS is usually due to Aspergillus or Zygomycetes species. These fungal spores are inhaled and germinated within the nose and paranasal sinuses; then fungal hyphae invade submucosal blood vessels leading to vasculitis and tissue necrosis. Either direct or vascular extension may occur leading to advanced condition (rhino-orbito-cerebral mucor mycosis).2 In Covid-19 era, incidence of AIFS has increased without explanation, may be due to immunosuppressed state, high ferritin level associated with SARS-CoV-2, and prolonged hospitalisation with excessive steroid and oxygen therapy utilisation; in addition to standard risk factors for AIFS.3

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